Infusion Reactions; Capillary Leak Syndrome; Visual Loss
Serious Infusion Reactions
Serious and fatal infusion reactions. Administer denileukin diftitox in a facility equipped and staffed for cardiopulmonary resuscitation. Immediately stop and permanently discontinue the drug for serious infusion reactions.
Capillary Leak Syndrome
Capillary leak syndrome resulting in death. Monitor weight, edema, blood pressure and serum albumin levels prior to and during denileukin treatment.