Toxicity in Hepatic Impairment
This drug in combination with capecitabine is contraindicated in patients with AST or ALT > 2.5 x ULN or bilirubin >1 x ULN due to increased risk of toxicity and neutropenia related death See Contraindications and Warnings and Precautions.
Patient counseling
Package inserts
Additional information
Updated: January 2018
Disclaimer: This information presents a SUMMARY of Black Box data from product information labeling and does not address additional warnings, precautions, or other important safety data in the product insert. Patient care decisions SHOULD NOT be made without reviewing the most recent product information insert, which may be obtained from the manufacturer. This table may not be complete as it was prepared using product information from package inserts. It is periodically updated with supplemental information from FDA safety alerts, the FDA labeling announcements, and new drug approvals.
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