All Dexmethylphenidate, Methylphenidate Products

• Chronic abusive use can lead to a marked tolerance and psychological dependence with varying degree of abnormal behavior
• Frank psychotic episodes can occur, especially with parenteral abuse.
• CNS stimulants, including Focalin, other methylphenidate-containing products, and amphetamines, have a high potential for abuse and dependence. Assess the risk of abuse prior to prescribing and monitor for signs of abuse and dependence while on therapy.

Methylphenidate Products: Concerta, Cotempla XR-ODT, Jornay PM, Metadate, Ritalin, Daytrana

Dexmethylphenidate Products: Focalin

• Should be given cautiously to patients with a history of drug dependence or alcoholism.
• Careful supervision required during drug withdrawal from abusive use since severe depression may occur.
• Withdrawal following chronic therapeutic use may unmask symptoms of the underlying disorder that may require follow-up. 

Methylphenidate Products: Methylin Products

• Should be given cautiously to emotionally unstable patients, such as those with a history of drug dependence or alcoholism, because such patients may increase dosage on their own initiative.
• Careful supervision required during drug withdrawal, since severe depression as well as the effects of chronic over activity can be unmasked.
• Long term follow-up may be required because of the patient's basic personality disturbances.

Serdexmethylphenidate/Dexmethylphenidate Capsules

• CNS stimulants, including AZSTARYS, other methylphenidatecontaining products, and amphetamines, have a high potential for abuse and dependence.
• Assess the risk of abuse prior to prescribing, and monitor for signs of abuse and dependence while on therapy.