BlackBoxRX
 
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Muromonab

Prior to Initiation of Therapy

  • Should be administered under supervision of Experienced Personnel in Equipped Facility (for cardiopulmonary resuscitation)
  • Anaphylactic and anaphylactoid reactions may occur following administration of any dose or course.
  • Cardiotoxicity, CNS & Systemic Reactions: potentially life-threatening reactions including pulmonary edema, shock, cardiovascular collapse, cardiac/respiratory arrest, seizures, coma, cerebral edema, cerebral herniation, blindness and paralysis.
  • Cytokine Release Syndrome

MONITORING RECOMMENDATIONS RELATED TO BLACK BOX DATA

  • Fluid status carefully monitored at baseline and during therapy
  • Pretreatment with methylprednisolone to minimized Cytokine Release Syndrome

Package Inserts

Muromonab

Additional Information

Updated January 2018