Streptomycin

Neurotoxicity: Nephrotoxicity

Neurotoxicity

• Risk of severe neurotoxic reactions is sharply increased in patients with impaired renal dysfunction or pre-renal

Nephrotoxicity

• Avoid concurrent use of nephrotoxic/neurotoxic drugs

MONITORING RECOMMENDATIONS RELATED TO BLACK BOX DATA

• Renal function shuld be monitored carefully and patients with reduced function should have reduced doses.
• Peak serum concentrations in patients with renal dysfunctions < 20>

Patient Counseling Information

• Streptomycin

Package Inserts

Streptomycin

Additional Information

• Pub Med -Streptomycin and Neurotoxicity
• Pub Med - Streptomycin and Nephrotoxicity