Infusion Reactions; Capillary Leak Syndrome; Visual Loss
Serious Infusion Reactions
- Serious and fatal infusion reactions. Administer denileukin diftitox in a facility equipped and staffed for cardiopulmonary resuscitation. Immediately stop and permanently discontinue the drug for serious infusion reactions.
Capillary Leak Syndrome
- Capillary leak syndrome resulting in death. Monitor weight, edema, blood pressure and serum albumin levels prior to and during denileukin treatment.
- Loss of visual acuity and color vision.
Patient Counseling Information
Updated January 2018