Ixabepilone

Toxicity in Hepatic Impairment

• This drug in combination with capecitabine is contraindicated in patients with AST or ALT > 2.5 x ULN or bilirubin >1 x ULN due to increased risk of toxicity and neutropenia related death See Contraindications and Warnings and Precautions.

Patient Counseling Information

• Ixempra

Package Inserts

Ixabepilone

Additional Information

• PubMed - Ixabepilone and Toxicity in Hepatic Impairment