BlackBoxRX
 
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Norethindrone (Oral) *

Risk of Cardiovascular Disease; Visual Abnormalities

Cardiovascular Disorders 

  • Patients with risk factors for arterial vascular disease (e.g., hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (e.g., personal history or family history of VTE, obesity, and systemic lupus erythematosus) should be managed appropriately.


Visual Abnormalities 

  • Discontinue medication pending examination if there is a sudden partial or complete loss of vision or if there is sudden onset of proptosis, diplopia, or migraine. If examination reveals papilledema or retinal vascular lesions, medication should be discontinued.

Package Inserts

Norethindrone

Updated January 2018