Anaphylaxis

• Anaphylaxis has been reported after administration of KALBITOR. Because of the risk of anaphylaxis, KALBITOR should only be administered by a healthcare professional with appropriate medical support to manage anaphylaxis and hereditary angioedema.
• Healthcare professionals should be aware of the similarity of symptoms between hypersensitivity reactions and hereditary angioedema and patients should be monitored closely.
• Do not administer KALBITOR to patients with known clinical hypersensitivity to KALBITOR. [ see Contraindications (4), Warnings and Precautions (5.1), and Adverse Reactions (6)]