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Sotalol (Intravenous)

Life Threatening Proarrhythmia

  • Sotalol can cause life threatening ventricular tachycardia associated with QT interval prolongation.
  • To minimize the risk of drug induced arrhythmia, initiate or uptitrate intravenous sotalol in a facility that can provide continuous electrocardiographic monitoring and cardiac resuscitation¬†[see Dosage and Administration (2.3) and Warnings and Precautions (5.1)]
  • Do not initiate intravenous sotalol therapy if the baseline QTc is longer than 450 ms. If the QTc prolongs to 500 ms or greater, reduce the dose or discontinue.

Package Inserts

Sotalol (Intravenous)

Updated April 2020