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Post Transplant Lymphoproliferative Disorder, Other Malignancies, And Serious Infections

  • Increased risk for developing post-transplant lymphoproliferative disorder (PTLD), predominantly involving the central nervous system.
  • Recipients wthout immunity to Epstein-Barr virus (EBV) are at a particularly increased risk; therefore, use in EBV seropositive patients only.
  • Do not use this drug in transplant recipients who are EBV seronegative or with unknow EBV serostatus [See Contraindications and Warnings and Precautions]
  • Increased suseptibility to infection and the possible development of malignancies may result rom immunosuppression. [See Warnings and Precautions]
  • Only physicians experienced in immunosuppressive therapy and management of kidney transplant patients should prescribe belatacept. The physician responsible fpr maintenance therapy should have complete information requisite for the follow-up of the patient.
  • Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and suportive medical resources.
  • Use in liver transplant patients is not recommended due to increased risk of graft loss and death. [See Warnings and Precautions]


Approved Risk Evaluation and Mitigation Strategies (REMS)


Patient Counseling Information

Medication Guides

Patient Medication Guide

Package Inserts


Updated January 2018