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Dacarbazine

Hemopoietic Depression; Hepatic Necrosis Risk

  • Should be administered under supervision of a qualified physician experience in the use of cancer chemotherapy.
  • Hemopoietic depression is the most common toxicity
  • Hepatic Necrosis has been reported
  • Carcinogen, Teratogen based on animal studies
  • Assessment of Benefit/Risk ratio should be considered in each patient

MONITORING RECOMMENDATIONS RELATED TO BLACK BOX DATA

  • Careful monitoring of red blood cells, white blood cells and platelet levels.

Package Inserts

Dacarbazine

Additional Information

Updated January 2018