We highly recommend enabling Javascript while using the BlackBoxRX site.
Mefloquine
Neuropsychiatric Events
Mefloquine may cause neuropsychiatric adverse reactions that can persist after mefloquine has been discontinued.
Mefloquine should not be prescribed for prophylaxis in patients with major psychiatric disorders. During prophylactic use, if psychiatric or neurologic symptoms occur, the drug should be discontinued and an alternative medication should be substituted
