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Buprenorphine (Subdermal Implant)

Implant Migration, Protrusion, Expulsion, and Nerve Damage Associated with Insertin and Removal

  • Insertion and removal of PROBUPHINE are associated with the risk of implant migration, protrusion, expulsion, and nerve damage resulting from the procedure.

PROBUPHINE is available only through a restricted program called the PROBUPHINE REMS Program.


FDA and Industry Communications

Index to FDA Drug Safety Information

Approved Risk Evaluation and Mitigation Strategies (REMS)

PROBUPHINE (Buprenorphine Hydrochloride) Subdermal Implant

Patient Counseling Information

Medication Guides

Patiient Medication Guide - PROBUPHINE

Package Inserts

Buprenorphine

 

Updated June 2016