Aspirin/Caffeine/Dihydrocodeine

Death Related to Ultra-Rapid Metabolism of Codeine to Morphine

  • Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.

Patient counseling

Communications

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Keywords: Synalgos-DC
Updated: October 2018