Thrombocytopenia and Glomerulonephritis

Thrombocytopenia

• TEGSEDI causes reductions in platelet count that may result in sudden and unpredictable thrombocytopenia, which can be lifethreatening. Testing prior to treatment and monitoring during treatment is required.

Glomerulonephritis

• TEGSEDI can cause glomerulonephritis that may require immunosuppressive treatment and may result in dialysisdependent renal failure. Testing prior to treatment and monitoring during treatment is required.