Angiotensin II Antagonists, ACE Inhibitors (Aliskiren, Azilsartan, Benazepril, Candesartan, Captopril, Enalapril, Eprosartan, Fosinopril, Irbesartan, Lisinopril, Moexipril, Olmesartan, Perindopril, Quinapril, Ramipril, Telmisartan, Trandolapril, Valsartan)

Use in Pregnancy, Fetal Toxicity

• When pregnancy is detected, these drugs should be discontinued as soon as possible.
• Drugs that act directly on the renin-angiotensin system can cause injury and death to developing fetus.
  

FDA and Industry Communications

• Ongoing Safety REview Completed (June 2011)
• Ongoing Safety Review for Cancer Risk (July 2010)
• Olmesartan: Ongoing Safety Review (June 2010)

Medication Guides

Patient Medication Guides

Package Inserts

Angiotensin II Antagonist, ACE Inhibitors

Additional Information

• Pub Med - Angiotensin II Antagonists in Pregnancy
• Pub Med - ACE Inhibitors in Pregnancy