Left Ventricular Dysfunction and Embryo-Fetal Toxicity
Left Ventricular Dysfunction
- MARGENZA may lead to reductions in left ventricular ejection fraction (LVEF). Evaluate cardiac function prior to and during treatment. Discontinue MARGENZA treatment for a confirmed clinically significant decrease in left ventricular function [see DOSAGE AND ADMINISTRATION (2.2), WARNINGS AND PRECAUTIONS (5.1), and ADVERSE REACTIONS (6.1)].
Patient Counseling Information
Updated January 2022