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Drospirenone/Estetrol Kit

Cigarette Smoking and Serious Cardiovascular Events

  • Cigarette smoking increases the risk of serious cardiovascular events from combined hormonal contraceptive (CHC) use. This risk increases with age, particularly in females over 35 years of age, and with the number of cigarettes smoked. For this reason, CHCs, including NEXTSTELLIS, are contraindicated in females who are over 35 years of age and smoke. [See CONTRAINDICATIONS (4) and WARNINGS AND PRECAUTIONS (5.1)]

Patient Counseling Information

Package Inserts

Drospirenone/Estetrol Kit

Updated May 2021