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Ifosfamide

Urotoxicity; Myelosuppression; CNS Toxicity

  • Use by experienced physician with cancer chemotherapy

Urotoxicity

  • Hemorraghic cystitis have been reported with use. 
  • May require discontinuation.

CNS Toxicity

  • Confusion, coma have been reported with use.
  • May require discontinuation

Myelosuppression

  • Maybe severe, and dose related.

MONITORING RECOMMENDATIONS RELATED TO BLACK BOX DATA

  • Hematological profile monitored prior to each dose regularly during therapy
  • Urinalysis (presence of red blood cells) prior to each dose and monitored regularly during therapy
  • Urotoxicity and CNS toxicity may require discontinuation of use.

Package Inserts

Ifosfamide

Additional Information

Updated January 2018